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Shixiong ZHANG

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City University of Hong Kong   Associate professor  

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Shixiong Zhang is an Associate Professor in the School of Computer Science and Technology at Xidian University, starting from December 2020. He spent three years (2017-2020) obtaining his Ph.D. in Computer Science under the mentorship of Dr. Ka-Chun Wong from the City University of Hong Kong. He was previously a research trainee in the Lab of Prof. Jiang Qian at the Johns Hopkins University School of Medicine. His broad research interests include bioinformatics, computational biology, machine learning, and computational intelligence.


E-mail: zhangsx AT xidian.edu.cn


Selected Publications

For more publications, you may check out [ResearchGate] or [Google Scholar].

(* Corresponding  authorship)

[11] Risheng Lu, Shixiong Zhang*, & Lin Gao*. (2025) Disentangling the over-integration of single-cell and spatial multiomics data with transfer learning, Big Data Mining and Analytics, DOI:10.26599/BDMA.2025.9020112. [IF 2025 = 6.2] [CCF-T1]

[10] Zeyu Yan, Yifei Yao, Xuanbing Wen, Shixiong Zhang*, Juli Zhang*, & Kai Fan*. (2025) LADSG: Label-anonymized distillation and similar gradient substitution for label privacy in vertical federated learning, International Conference on Collaborative Computing: Networking, Applications and Worksharing (EAI CollaborateCom 2025)[CCF-C]

[9] Zhenglong Cheng, Risheng Lu, & Shixiong Zhang*. (2025) scMGCL: accurate and efficient integration representation of single-cell multiomics data, Bioinformatics, 41(7), btaf392. [PDF] [IF 2025 = 5.4][CCF-A]

[8] Meng Lan, Shixiong Zhang*, & Lin Gao*. (2023) Efficient generation of paired single-cell multiomics profiles by deep learning. Advanced Science, 10(21), 2301169. [PDF] [IF 2021 = 17.521]

[7] Shixiong Zhang*, Xiangtao Li, Jiecong Lin, Qiuzhen Lin, & Ka-Chun Wong. (2023) Review of single-cell RNA-seq data clustering for cell type identification and characterization. RNA29(5), 517-530. [PDF] [IF 2021 = 5.636]

[6] Shixiong Zhang, Xiangtao Li, Qiuzhen Lin, Jiecong Lin, Ka-Chun Wong*. (2020) Uncovering the key dimensions of high-throughput biomolecular data using deep learning. Nucleic Acids Research, 48(10), e56, 2020. [PDF] [IF 2020 = 16.971]

[5] Shixiong Zhang, Xiangtao Li, Qiuzhen Lin, Ka-Chun Wong*. (2019) Nature-inspired compressed sensing for transcriptomic profiling from random composite measurement. IEEE Transactions on Cybernetics, 51(9), 4476-4487. [PDF] [IF 2020 = 11.079]

[4] Shixiong Zhang, Xiangtao Li, Qiuzhen Lin, Ka-Chun Wong*. (2019) Synergizing CRISPR/Cas9 off-target predictions for ensemble insights and practical applications. Bioinformatics. 35 (7), 1108-1115. [PDF] [IF 2019 = 5.610]

[3] Wenyu Zhang (Supervisor), Shixiong Zhang, Shuai Zhang* (2018). Two-factor high-order fuzzy-trend fts model based on BSO-FCM and improved KA for TAIEX stock forecasting. Nonlinear Dynamics, 94(2), 1429-1446. [PDF] [IF 2018 = 4.604]

[2] Wenyu Zhang (Supervisor)Shixiong Zhang, Shuai Zhang*, Dejian Yu, Ningning Huang. (2018). A novel method based on FTS with both GA-FCM and multifactor BPNN for stock forecasting. Soft Computing, 23 (16), 6979-6994. [PDF] [IF 2018 = 2.784]

[1] Wenyu Zhang* (Supervisor), Shixiong Zhang, Shuai Zhang, Dejian Yu, Ningning Huang. (2017). A multi-factor and high-order stock forecast model based on type-2 FTS using cuckoo search and self-adaptive harmony search. Neurocomputing, 240, 13-24. [PDF] [IF 2017 = 3.241]


Group Members:

Graduate Student

Zeyu Xing (Digital Pathology, 2025- )

Zhenglong Cheng (Multiomics, 2024- )

Risheng Lu (Co-supervised, Multiomics, 2023- )

Undergraduate

Hengyong Xu (2025-)

Chuanyang Zhou (2023-)


Alumni:

Yi Lu, BSc., 2021- 2025 (Sequence Analysis and LLM, National Scholarship 2024) --> CityUHK (PhD Programme)

Meng Lan, MSc., 2021-2024 (Co-supervised, National Scholarship 2023) --> Alibaba DAMO Academy


Scholarships and Awards

Research Tuition Scholarship (2018, 2019), City University of Hong Kong

Outstanding Academic Performance Award (2018, 2019, 2020), City University of Hong Kong

Outstanding Master's Dissertation Award of Zhejiang Province (2017)

National Scholarship (2016)


Academic Service                         

Journal Editorial Board Memberships

Heliyon (Associate Editor)

Cells (Topical Advisory Panel Member)

Journal Guest Editorships

Cells (Guest Editor)

Mathematical Biosciences and Engineering (Leading Guest Editor)

Conference Chairships

IEEE ICCCS 2022 Session Chair

ISCMI 2023 Program Co-chair 2022 Publications Co-chair

ISMSI 2023 2022 Organizing Co-chair

Conference Program Committee Memberships

ICIC 2022 (PC) 2021 (PC)                                                    

ICBRA 2022 (TC) 2021 (TC)                        

ICONIP 2022 (PC) 2021 (PC) 2020 (PC)                                                             


Education Background

2010.09 2014.06

  • Zhejiang University of Finance & Economics
  • Information Management and Information System
  • B.Sc.

2014.09 2017.03

  • Zhejiang University of Finance & Economics
  • Management Statistics
  • M.Sc.

2017.09 2020.08

  • City University of Hong Kong
  • Computer Science
  • Ph.D

Work Experience

2019.11 2020.04
  • Johns Hopkins University
  • Medical School
  • Research Visiting
2020.12 Now
  • Xidian University
  • School of Computer Science and Technology
  • Associate Professor
  • On Duty

Social Affiliations

  • No Content